Home > Sandwich ELISA Kits > Human B-Cell Activation Factor Receptor (BAFFR) ELISA Kit

Product Name:

Human B-Cell Activation Factor Receptor (BAFFR) ELISA Kit

Cat.#:

JL10332

Regulatory Status:

RUO

Alternative:

CD268; TNFRSF13C; TNFRSF13-C; BAFF receptor (B-cell activating factor receptor; BAFF-R); BAFFR; BR3; Tumor Necrosis Factor Receptor Superfamily Member 13C;BLyS receptor 3 (BR3)

Detection Method:

ELISA

Assay Type:

Sandwich

Detection Range:

0.156-10ng/mL

Sensitivity:

0.075ng/mL

Specificity:

This kit recognizes Human BAFFR in samples. No significant cross-reactivity or interference between Human BAFFR and analogues was observed.

Sample Type:

tissue homogenates;cell lysates and other biological fluids

Assay Procedure:

Research Area:

Cancer

Size & Price:

Human A1BG Polyclonal Antibody

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Product Datasheets

Instruction:

Data
Citations
Sequence / 3D

| BAFFR

B-Cell Activation Factor Receptor (BAFFR) is a membrane protein of the TNF receptor superfamily which recognizes BAFF, an essential factor for B cell maturation and survival.It is encoded by the TNFRSF13C gene.B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.In B cell maturation, due to regulation by BAFF-R, only a limited amount of B-cell will survive.

| Repeatability

Intra-assay Precision (Precision within an assay)：CV% < 10%; Inter-assay Precision (Precision between assays)：CV% < 10%

| Recovery

The recovery of Human BAFFR spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type	Range(%)	Average Recovery(%)
Tissue Homogenates(n=8)	93-105	103
Cell Lysates(n=8)	96-108	105

| Linearity

Samples were spiked with high concentrations of Human BAFFR and diluted with Universal Diluent to produce samples with values within the range of the assay.

		Tissue Homogenates(n=4)	Cell Lysates(n=4)
1 : 2	Range (%)	88-96	90-110
1 : 2	Average (%)	93	96
1 : 4	Range (%)	86-108	105-115
1 : 4	Average (%)	97	108